EFL066 - Islet Autoantibodies

<p><span style="color: rgb(44, 42, 41);">For our 66th episode, we review a recent&nbsp;</span><em style="color: rgb(44, 42, 41);">Journal of the Endocrine Society</em><span style="color: rgb(44, 42, 41);">&nbsp;(JES) article that looks at the frequency of positive islet antibodies in a population of adults without diabetes. While that may initially seem like an unusual article choice, we found it to be quite helpful in an era where we now have a therapeutic option to delay the onset of clinical type 1 diabetes when we can identify people early enough. That treatment option naturally raises questions about how we can find such patients and the risk of false-positive results with these antibodies. Host Chase Hendrickson, MD, MPH, MHCC, from Vanderbilt University talks with regular contributor Steven D. Wittlin, MD, from the University of Rochester Medical Center, and guest expert Raghu G. Mirmira, MD, PhD, from the University of Chicago. They discuss&nbsp;</span><a href="https://doi.org/10.1210/jendso/bvaf095" rel="noopener noreferrer" target="_blank" style="color: rgb(0, 45, 114);"><strong>“Prevalence of Islet Autoantibodies in Adults Without Diabetes”</strong></a><span style="color: rgb(44, 42, 41);">&nbsp;by Pauley et al, published in the August 2025 issue of JES.</span></p>

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